<ArticleSet>
<Article>
<Journal>
<PublisherName>Trauma Research Center</PublisherName>
<JournalTitle>Bulletin of Emergency And Trauma</JournalTitle>
<Issn>2322-2522</Issn>
<Volume>6</Volume>
<Issue>3 JUL</Issue>
<PubDate>
<Year>2018</Year>
<Month>06</Month>
<Day>28</Day>
</PubDate>
</Journal>
<ArticleTitle>Healing Effects of Dried and Acellular Human Amniotic Membrane and Mepitelas for Coverage of Skin Graft Donor Areas; A Randomized Clinical Trial</ArticleTitle>
<FirstPage>195</FirstPage>
<LastPage>200</LastPage>
<Language>ENGLISH</Language>
<AuthorList>
<Author>
<FirstName>Masoumeh</FirstName>
<LastName>Nouri</LastName>
<Affiliation>1 Ph.D. of Molecular genetics, Department of Regenerative Biomedicine, Cell Science Research Center, Royan Institute, Tehran, Iran. masoume.nouri2002@gmail.com</Affiliation>
</Author>
<Author>
<FirstName>Marzieh</FirstName>
<LastName>Ebrahimi</LastName>
</Author>
<Author>
<FirstName>Tooran</FirstName>
<LastName>Bagheri</LastName>
</Author>
<Author>
<FirstName>Mohammad Javad</FirstName>
<LastName>Fatemi</LastName>
</Author>
<Author>
<FirstName>Arash</FirstName>
<LastName>Najafbeygi</LastName>
</Author>
<Author>
<FirstName>Shirin</FirstName>
<LastName>Araghi</LastName>
</Author>
<Author>
<FirstName>Maryam</FirstName>
<LastName>Molaee</LastName>
</Author>
</AuthorList>
<History>
<PubDate>
<Year>2018</Year>
<Month>01</Month>
<Day>24</Day>
</PubDate>
<PubDate>
<Year>2018</Year>
<Month>03</Month>
<Day>21</Day>
</PubDate>
<PubDate>
<Year>2018</Year>
<Month>03</Month>
<Day>19</Day>
</PubDate>
</History>
<Abstract>Objective: To compare the healing effects of dried and acellular human amniotic membrane and Mepitel for coverage of split-thickness graft donor site (STGDS).  Methods: Twenty patients who underwent STGDS regeneration surgery in identical anatomic regions were enrolled in this randomized controlled clinical trial conducted in Hazrate Fatemeh hospital (Iran). Patients were randomly assigned in 3 groups of wound dressing; group A by Mepitel, group B AmiCare (Dried amniotic membrane) and group C OcuReg-A (Acellular amniotic membrane). Re-epithelization rate (healing time), pain sensation, scar formation and infection rate were assessed till complete healing was achieved.Results: Our results showed no significant difference between Amicare, OcuReg-A and Mepitel in the features analyzed by us including: Re-epithelization rate (healing time) P value; 0.573, Pain sensation P value: day 4 th: 0.131, day8 th: 0.93 and day 12 th: 0.365, Scar formation P value>0.05 and Infection rate.Conclusion: Our findings confirmed the safety and efficacy of AmiCare (dried amniotic membrane) and OcuReg-A (Acellular amniotic membrane) in treatment of split-thickness donor site in comparison with Mepitel as a standard wound dressing.Trial registration number: IRCT201511118177N12.</Abstract>
<ObjectList>
<Object>
<Param>Split-thickness donor site</Param>
</Object>
<Object>
<Param>Dried amniotic membrane</Param>
</Object>
<Object>
<Param>Acellular amniotic membrane</Param>
</Object>
<Object>
<Param>Mepitel</Param>
</Object>
<Object>
<Param>Re-epithelization</Param>
</Object>
</ObjectList>
</Article>
</ArticleSet>